Production of leptospiral LipL32 antigen in Pichia pastoris and its use in an enzyme-linked immunosorbent assay
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چکیده
منابع مشابه
Production of Leptospiral LipL32 Antigen in Pichia pastoris and Its Use in an Enzyme-Linked Immunosorbent Assay
The production of recombinant LipL32 protein using Escherichia coli has been used extensively for the development of vaccines and diagnostic tests for leptospirosis. However, E. coli has demonstrated limitations, including low yield and lack of post-translational modifications. In this study, rLipL32 was produced in eukaryotic expression system (Pichia pastoris) and evaluated the antigen by enz...
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ژورنال
عنوان ژورنال: Brazilian Archives of Biology and Technology
سال: 2014
ISSN: 1678-4324
DOI: 10.1590/s1516-89132014005000001